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A Highly Pathogenic #Avian #H7N9 #Influenza Virus Isolated from A #Human Is Lethal in Some #Ferrets Infected via #Respiratory #Droplets (Cell Host Microbe, abstract)

Title : A Highly Pathogenic #Avian #H7N9 #Influenza Virus Isolated from A #Human Is Lethal in Some #Ferrets Infected via #Respiratory #Drop...

20 Nov 2017

#HK CHP notified of #human case of #avian #influenza A(#H5N6) in #Guangxi (Nov. 20 ‘17)


Title: #HK CHP notified of #human case of #avian #influenza A(#H5N6) in #Guangxi.

Subject: Avian Influenza, H5N6 subtype, human case in China, Guangxi province.

Source: Centre for Health Protection, Hong Kong PRC SAR, full page: (LINK).

Code: [     ]

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CHP notified of human case of avian influenza A(H5N6) in Guangxi

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The Centre for Health Protection (CHP) of the Department of Health (DH) today (November 20) received notification of an additional human case of avian influenza A(H5N6) in Guangxi from the National Health and Family Planning Commission, and again urged the public to maintain strict personal, food and environmental hygiene both locally and during travel.

The case involved a 33-year-old man from Guigang. He developed symptoms on November 7 and was hospitalised on November 12. He is now in a critical condition. The patient had contact with live poultry and exposure to live poultry markets before the onset of symptoms.

"Based on the seasonal pattern of avian influenza viruses, their activity in the Mainland is expected to increase in winter. The public should avoid contact with poultry, birds and their droppings and should not visit live poultry markets and farms to prevent avian influenza," a spokesman for the CHP said.

From 2014 to date, 17 human cases of avian influenza A(H5N6) have been reported by the Mainland health authorities.

"All novel influenza A infections, including H5N6, are notifiable infectious diseases in Hong Kong," the spokesman said.

Travellers to the Mainland or other affected areas must avoid visiting wet markets, live poultry markets or farms. They should be alert to the presence of backyard poultry when visiting relatives and friends. They should also avoid purchasing live or freshly slaughtered poultry, and avoid touching poultry/birds or their droppings. They should strictly observe personal and hand hygiene when visiting any place with live poultry.    

Travellers returning from affected areas should consult a doctor promptly if symptoms develop, and inform the doctor of their travel history for prompt diagnosis and treatment of potential diseases. It is essential to tell the doctor if they have seen any live poultry during travel, which may imply possible exposure to contaminated environments. This will enable the doctor to assess the possibility of avian influenza and arrange necessary investigations and appropriate treatment in a timely manner.

While local surveillance, prevention and control measures are in place, the CHP will remain vigilant and work closely with the World Health Organization and relevant health authorities to monitor the latest developments.

The CHP's Port Health Office conducts health surveillance measures at all boundary control points. Thermal imaging systems are in place for body temperature checks on inbound travellers. Suspected cases will be immediately referred to public hospitals for follow-up.

The display of posters and broadcasting of health messages in departure and arrival halls as health education for travellers is under way. The travel industry and other stakeholders are regularly updated on the latest information.

The public should maintain strict personal, hand, food and environmental hygiene and take heed of the advice below if handling poultry:

  • Avoid touching poultry, birds, animals or their droppings;
  • When buying live chickens, do not touch them and their droppings. Do not blow at their bottoms. Wash eggs with detergent if soiled with faecal matter and cook and consume the eggs immediately. Always wash hands thoroughly with soap and water after handling chickens and eggs;
  • Eggs should be cooked well until the white and yolk become firm. Do not eat raw eggs or dip cooked food into any sauce with raw eggs. Poultry should be cooked thoroughly. If there is pinkish juice running from the cooked poultry or the middle part of its bone is still red, the poultry should be cooked again until fully done;
  • Wash hands frequently, especially before touching the mouth, nose or eyes, before handling food or eating, and after going to the toilet, touching public installations or equipment such as escalator handrails, elevator control panels or door knobs, or when hands are dirtied by respiratory secretions after coughing or sneezing; and
  • Wear a mask if fever or respiratory symptoms develop, when going to a hospital or clinic, or while taking care of patients with fever or respiratory symptoms.

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The public may visit the CHP's pages for more information:

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Ends/Monday, November 20, 2017  / Issued at HKT 18:05  / NNNN

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Keywords: HK PRC SAR; Updates; China; H5N6; Avian Influenza; Human; Guangxi.

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Highly pathogenic #avian #influenza #H5N8, #Korea (Rep. of) [fifteen #poultry #outbreaks] (#OIE, Nov. 20 ‘17)


Title: Highly pathogenic #avian #influenza #H5N8, #Korea (Rep. of) [fifteen #poultry #outbreaks].

Subject: Avian Influenza, H5N8 subtype, poultry epizootics in South Korea.

Source: OIE, full page: (LINK).

Code: [     ]

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Highly pathogenic avian influenza H5N8, Korea (Rep. of)

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Information received on 20/11/2017 from Dr Oh Soon-Min, Director - Chief Veterinary Officer, General Animal Health Division, Ministry of Agriculture, Food and Rural Affairs (MAFRA), SEJONG-SI, Korea (Rep. of)

  • Summary
    • Report type     Follow-up report No. 3 (Final report)
    • Date of start of the event     06/02/2017
    • Date of confirmation of the event     06/02/2017
    • Report date     20/11/2017
    • Date submitted to OIE     20/11/2017
    • Date event resolved     13/10/2017
    • Reason for notification     Recurrence of a listed disease
    • Date of previous occurrence     04/2016
    • Manifestation of disease     Clinical disease
    • Causal agent     Highly pathogenic avian influenza virus
    • Serotype     H5N8
    • Nature of diagnosis     Laboratory (advanced)
    • This event pertains to     the whole country
  • Summary of outbreaks    
    • Total outbreaks: 15
      • Total animals affected: Species     - Susceptible     - Cases     - Deaths     - Killed and disposed of  - Slaughtered
        • Birds     - 1327     - **     - 0     - 1327     - 0
      • Outbreak statistics: Species     - Apparent morbidity rate     - Apparent mortality rate     - Apparent case fatality rate     - Proportion susceptible animals lost*
        • Birds     - **     - 0.00%     - **     - 100.00%
          • *Removed from the susceptible population through death, destruction and/or slaughter
          • **Not calculated because of missing information
  • Epidemiology
    • Source of the outbreak(s) or origin of infection    
      • Unknown or inconclusive


(...)

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Keywords: OIE; Updates; Avian Influenza; H5N8 ; Poultry; South Korea.

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#Plague #Outbreak in #Madagascar – External #Situation #Report No. 11, November 17 2017 (@WHO AFRO, edited)


Title: #Plague #Outbreak in #Madagascar – External #Situation #Report No. 11, November 17 2017.

Subject: Plague (Pneumonic, Bubonic) Outbreak in Madagascar, current situation.

Source: World Health Organization (WHO), Office for Africa Region, full PDF file: (LINK).

Code: [     ]

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Plague Outbreak in Madagascar – External Situation Report No. 11, November 17 2017

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Keywords: WHO; Updates; Plague; Madagascar.

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#Plague #Outbreak in #Madagascar – Situation #Report, November 16 2017 (Edited)


Title: #Plague #Outbreak in #Madagascar – Situation #Report, November 16 2017.

Subject: Plague (Pneumonic, Bubonic) Outbreak in Madagascar, current situation.

Source: Ministry of Interior of Madagascar, full PDF file: (LINK). Article in French.

Code: [     ]

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Plague Outbreak in Madagascar – Situation Report, November 16 2017

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Keywords: Madagascar; Updates; Plague.

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Today is #WorldChildrensDay! (@WHO)


Title: Today is #WorldChildrensDay!.

Subject: Day of awareness for children welfare and health.

Source: World Health Organization (WHO), full page: (LINK).

Code: [ EDU ]

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Keywords: WHO; Updates; Society; Public Health.

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One New Confirmed #MERS #Coronavirus case reported by #Saudi Arabia (MoH, Nov. 20 ‘17)


Title: One New Confirmed MERS Coronavirus case reported by Saudi Arabia.

Subject: Middle East Respiratory Syndrome in Saudi Arabia, daily update.

Source: Saudi Arabia Ministry of Health, full page: (LINK).

Code: [     ]

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MOH: '1 New Confirmed Coronavirus Case Recorded'

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20 November 2017

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New Case Reported:

[Sex, Age, Citizenship, Resident in, Health Status, Note]

  1. Male, 63, Saudi, Bisha, stable; *

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{*} Primary (Direct contact with camels).

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Cumulative number of confirmed cases and deaths since 2012:

  • Total No. of Cases: 1747
  • Total No. of Deaths: 707
  • Patients currently under treatment: 7
  • Case-Fatality Rate: 40.4%

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Keywords: MERS-CoV; Updates; Saudi Arabia.

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Highly pathogenic #avian #influenza H5N6, #Korea (Rep. of) [a #poultry #outbreak (#OIE, Nov. 20 ‘17)


Title: Highly pathogenic #avian #influenza H5N6, #Korea (Rep. of) [a #poultry #outbreak.

Subject: Avian Influenza, H5N6 subtype, poultry epizootics in South Korea.

Source: OIE, full page: (LINK).

Code: [     ]

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Highly pathogenic avian influenza H5N6, Korea (Rep. of)

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Information received on 19/11/2017 from Dr Oh Soon-Min, Director - Chief Veterinary Officer, General Animal Health Division, Ministry of Agriculture, Food and Rural Affairs (MAFRA), SEJONG-SI, Korea (Rep. of)

  • Summary
    • Report type    Immediate notification
    • Date of start of the event    17/11/2017
    • Date of confirmation of the event    19/11/2017
    • Report date    19/11/2017
    • Date submitted to OIE    19/11/2017
    • Reason for notification    Recurrence of a listed disease
    • Date of previous occurrence    13/10/2017
    • Manifestation of disease    Clinical disease
    • Causal agent    Highly pathogenic avian influenza virus
    • Serotype    H5N6
    • Nature of diagnosis    Laboratory (advanced)
    • This event pertains to    the whole country
  • New outbreaks
    • Summary of outbreaks   
      • Total outbreaks: 1
        • Outbreak Location     •    JEOLLABUK-DO ( Gochang-gun, Chiryong-li, Heungduck-myun )
          • Total animals affected:    Species    - Susceptible    - Cases    - Deaths    - Killed and disposed of    - Slaughtered
            • Birds     - 12500     - 10     - 0     - 12500     - 0
        • Outbreak statistics:    Species    - Apparent morbidity rate    - Apparent mortality rate    - Apparent case fatality rate    - Proportion susceptible animals lost*
          • Birds    - 0.08%    - 0.00%    - 0.00%    - 100.00%
            • * Removed from the susceptible population through death, destruction and/or slaughter;
  • Epidemiology
    • Source of the outbreak(s) or origin of infection   
      • Unknown or inconclusive
  • Epidemiological comments   
    • Epidemiological investigation is ongoing
  • Control measures
    • Measures applied   
      • Movement control inside the country
      • Surveillance outside containment and/or protection zone
      • Surveillance within containment and/or protection zone
      • Screening
      • Traceability
      • Quarantine
      • Official destruction of animal products
      • Official disposal of carcasses, by-products and waste
      • Stamping out
      • Control of wildlife reservoirs
      • Disinfection
      • Vaccination prohibited
      • No treatment of affected animals
    • Measures to be applied   
      • No other measures
  • Diagnostic test results
    • Laboratory name and type    - Animal and Plant Quarantine Agency ( National laboratory )
      • Tests and results:    Species    - Test    - Test date    - Result
        • Birds    - reverse transcription - polymerase chain reaction (RT-PCR)    - 19/11/2017     - Positive
  • Future Reporting
    • The event is continuing. Weekly follow-up reports will be submitted.


(...)

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Keywords: OIE; Updates; Avian Influenza; H5N6 ; Poultry; S. Korea.

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It’s World Day of Remembrance for Road Traffic Victims. #RoadSafety is no accident (@WHO)


Title: It’s World Day of Remembrance for Road Traffic Victims. #RoadSafety is no accident.

Subject: Road Safety, awareness campaign.

Source: World Health Organization (WHO), full page: (LINK).

Code: [ EDU ]

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Keywords: WHO; Worldwide; Educational Materials; Public Health.

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#Avian #Influenza [#H5N1, #H5N6, #H7N9] – Weekly #Update No. 611, November 17 2017 (@WHO WPRO, edited)


Title: #Avian #Influenza [#H5N1, #H5N6, #H7N9] – Weekly #Update No. 611, November 17 2017.

Subject: Avian Influenza, H5 & H7 subtypes, global poultry panzootic and human cases in Asian Region.

Source: World Health Organization (WHO), Office for the Western Pacific Region, full PDF file: (LINK).

Code: [     ]

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Avian Influenza – Weekly Update No. 611, November 17 2017

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Keywords: Avian Influenza; H5N1; H5N6; H7N9; Human; Asia Region; WHO; Updates.

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#Influenza and other #Respiratory #Viruses #Research #References #Library– November 20 2017 Issue


Title: #Influenza and other #Respiratory #Viruses #Research #References #Library– November 20 2017 Issue.

Subject: Human and Animal Influenza Viruses, other respiratory pathogens research, weekly references library update.

Source: AMEDEO, homepage: (LINK).

Code: [  R  ]

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This Issue:

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    • How can we prepare better for influenza epidemics?
  1. DYER C.
    • Irish MP calls for key documents on Pandemrix to be handed to lawyers representing children with narcolepsy.
  2. GULLAND A.
    • Sixty seconds on . . . flu.
  3. COHEN DM, Kline J, May LS, Harnett GE, et al.
    • Accurate PCR Detection of Influenza A/B and RSV Using the Cepheid Xpert Flu+RSV Xpress Assay in Point-of-Care Settings: Comparison to Prodesse ProFlu.
      • J Clin Microbiol. 2017 Nov 15. pii: JCM.01237-17. doi: 10.1128/JCM.01237.
  4. NYKVIST M, Gillman A, Soderstrom Lindstrom H, Tang C, et al.
    • In vivo mallard experiments indicate that zanamivir has less potential for environmental influenza A virus resistance development than oseltamivir.
      • J Gen Virol. 2017 Nov 15. doi: 10.1099/jgv.0.000977.
  5. SEON SH, Choi JA, Yang E, Pyo S, et al.
    • Intranasal Immunization with an Attenuated Pep27 Mutant Provides Protection from Influenza Virus and Secondary Pneumococcal Infections.
      • J Infect Dis. 2017 Nov 14. doi: 10.1093.
  6. TE VELTHUIS AJW, Oymans J.
    • Initiation, elongation and realignment during influenza virus mRNA synthesis.
      • J Virol. 2017 Nov 15. pii: JVI.01775-17. doi: 10.1128/JVI.01775.
  7. WILLE M, Yin H, Lundkvist A, Xu J, et al.
    • RNAlater(R) is a viable storage option for avian influenza sampling in logistically challenging conditions.
      • J Virol Methods. 2017;252:32-36.
  8. LIU J, Yao L, Zhai F, Chen Y, et al.
    • Development and application of a triplex real-time PCR assay for the simultaneous detection of avian influenza virus subtype H5, H7 and H9.
      • J Virol Methods. 2017 Nov 9. pii: S0166-0934(17)30361.
  9. AINSLIE KEC, Shi M, Haber M, Orenstein WA, et al.
    • On the bias of estimates of influenza vaccine effectiveness from test-negative studies.
      • Vaccine. 2017 Nov 13. pii: S0264-410X(17)31539.
  10. COLE KS, Martin JM, Horne WT, Lin CJ, et al.
    • Differential gene expression elicited by children in response to the 2015-16 live attenuated versus inactivated influenza vaccine.
      • Vaccine. 2017 Nov 10. pii: S0264-410X(17)31235.
  11. PAN Y, Wang Q, Yang P, Zhang L, et al.
    • Influenza vaccination in preventing outbreaks in schools: A long-term ecological overview.
      • Vaccine. 2017 Nov 8. pii: S0264-410X(17)31525.
  12. PUIG-BARBERA J, Guglieri-Lopez B, Tortajada-Girbes M, Lopez-Labrador FX, et al.
    • Low influenza vaccine effectiveness and the effect of previous vaccination in preventing admission with A(H1N1)pdm09 or B/Victoria-Lineage in patients 60 years old or older during the 2015/2016 influenza season.
      • Vaccine. 2017 Nov 8. pii: S0264-410X(17)31529.
  13. PILLSBURY A, Quinn H, Cashman P, Leeb A, et al.
    • Active SMS-based influenza vaccine safety surveillance in Australian children.
      • Vaccine. 2017 Nov 8. pii: S0264-410X(17)31499.
  14. CROUSE QUINN S, Jamison AM, Freimuth VS, An J, et al.
    • Determinants of influenza vaccination among high-risk Black and White adults.
      • Vaccine. 2017 Nov 7. pii: S0264-410X(17)31491.
  15. OHANNESSIAN R, Yaghobian S, Verger P, Vanhems P, et al.
    • A systematic review of serious video games used for vaccination.
      • Vaccine. 2016 Aug 3. pii: S0264-410X(16)30646.
  16. BOYCE TG, Yogev R, DeVincenzo JP, Krilov LR, et al.
    • Confounding by Indication Limits Conclusions of Study of Palivizumab Effectiveness.

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Keywords: Research; Abstracts; Influenza References Library.

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